Fundamentals of SARS-CoV-2 Biosensors

COVID-19 diagnostic strategies based on advanced techniques are currently essential topics of interest, with crucial roles in scientific research. This book integrates fundamental concepts and critical analyses that explore the progress of modern methods for the detection of SARS-CoV-2

Five Insights for Avoiding Global Collapse

Looming environmental and social breaking points, like climate change and massive inequalities, are becoming increasingly apparent and large in scale. In this book, Gaya Herrington puts today’s key societal challenges in perspective. Her analysis, rooted in her research on a 50-year-old model of the world that forecasted the onset of global collapse right around the present time, brings some structure to what otherwise might feel like the overwhelming task of achieving genuine societal sustainability. Herrington's research, first published in 2020 in Yale‘s Journal of Industrial Ecology, went viral after it revealed empirical data tracked closely with the predictions of this world model, which was introduced in the 1972 best seller The Limits to Growth. Her book Five Insights for Avoiding Global Collapse contains an exclusive research update based on 2022 data and is written in a more personable and accessible style than the journal article. Herrington also elaborates more in this book on the many interlinkages between our economic, environmental, and social predicaments, and on what her findings indicate for future global developments. Herington lays out why “business as usual” is not a viable option for global society and identifies the root cause of this unsustainable path. Most importantly, her book teaches us what systemic changes humanity still has time to make to achieve a better tomorrow. A future in which society has transformed beyond the mere avoidance of collapse and is truly thriving

Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis

Systemic sclerosis (scleroderma) is an incurable connective tissue disease with an unclear etiology characterized by vasculopathy, dysregulation of the immune response, and progressive tissue fibrosis affecting the skin, lungs, digestive tract, heart, and kidneys. The collection of six original research manuscripts and five review articles included in this book highlights the most recent advances in this field and provides further elucidation of the pathogenesis, natural disease course, and treatment of this challenging disease

Lipolytic enzymes and hydrolytic rancidity

Lipolysis, the enzymic hydrolysis of milk lipids to free fatty acids and partial glycerides, is a constant concern to the dairy industry because of the detrimental effcts it can have on the flvor and other properties of milk and milk products. However, free fatty acids also contribute to the desirable flavor of milk and milk products when present at low concentrations and, in some cheeses, when present at high concentrations. The enzymes responsible for the detrimental effects of lipolysis are of two main types: those indigenous to milk, and those of microbial origin. The major indigenous milk enzyme is lipoprotein lipase. It is active on the fat in natural milk fat globules only after their disruption by physical treatments or if certain blood serum lipoproteins are present. The major microbial lipases are produced by psychrotrophic bacteria. Many of these enzymes are heat stable and are particularly significant in stored products. Human milk differs from cows' milk in that it contains two lipases, a lipoprotein lipase and a bile salt-stimulated lipase. The ability of the latter to cause considerable hydrolysis of ingested milk lipids has important nutritional implications